Endocrine Abstracts

Introduction: Bullous pemphigoid (BP) is an uncommon chronic, autoimmune, and subepidermal disease. It can be associated with drugs, u.v. irradiation, and X-ray therapy. There is a number of reports on bullous pemphigoid (BP) induced by DPP-IV inhibitors (vildagliptin, sitagliptin, saxagliptin). The enzyme DPP-IV degrades glucagon like peptide 1 (GLP-1), which is a potent stimulator of insulin production and secretion. DPP-IV (CD26), present as a cell surface molecule on immun...